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Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells

Background: Calcific aortic valve disease (CAVD) is a chronic inflammatory disease. Soluble extracellular matrix (ECM) proteins can act as damage-associated molecular patterns and may induce valvular inflammation. Matrilin-2 is an ECM protein and has been found to elevate the pro-osteogenic activity...

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Detalles Bibliográficos
Autores principales: The, Erlinda, Yao, Qingzhou, Zhang, Peijian, Zhai, Yufeng, Ao, Lihua, Fullerton, David A., Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072362/
https://www.ncbi.nlm.nih.gov/pubmed/32046115
http://dx.doi.org/10.3390/cells9020385