Cargando…
Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells
Background: Calcific aortic valve disease (CAVD) is a chronic inflammatory disease. Soluble extracellular matrix (ECM) proteins can act as damage-associated molecular patterns and may induce valvular inflammation. Matrilin-2 is an ECM protein and has been found to elevate the pro-osteogenic activity...
Autores principales: | The, Erlinda, Yao, Qingzhou, Zhang, Peijian, Zhai, Yufeng, Ao, Lihua, Fullerton, David A., Meng, Xianzhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072362/ https://www.ncbi.nlm.nih.gov/pubmed/32046115 http://dx.doi.org/10.3390/cells9020385 |
Ejemplares similares
-
Pro-inflammatory mediators released by activated monocytes promote aortic valve fibrocalcific activity
por: Zhang, Peijian, et al.
Publicado: (2022) -
Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions
por: The, Erlinda, et al.
Publicado: (2023) -
Up-regulation of Myocardial Klotho Expression to Promote Cardiac Functional Recovery in Old Mice following Endotoxemia
por: Li, Xueting, et al.
Publicado: (2023) -
Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3
por: The, Erlinda, et al.
Publicado: (2022) -
Elevated Expression of TLR2 in Aging Hearts Exacerbates Cardiac Inflammatory Response and Adverse Remodeling Following Ischemia and Reperfusion Injury
por: Zhai, Yufeng, et al.
Publicado: (2022)