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Uncovering Tumour Heterogeneity through PKR and nc886 Analysis in Metastatic Colon Cancer Patients Treated with 5-FU-Based Chemotherapy

Colorectal cancer treatment has advanced over the past decade. The drug 5-fluorouracil is still used with a wide percentage of patients who do not respond. Therefore, a challenge is the identification of predictive biomarkers. The protein kinase R (PKR also called EIF2AK2) and its regulator, the non...

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Detalles Bibliográficos
Autores principales: Ortega-García, María Belén, Mesa, Alberto, Moya, Elisa L.J., Rueda, Beatriz, Lopez-Ordoño, Gabriel, García, Javier Ángel, Conde, Verónica, Redondo-Cerezo, Eduardo, Lopez-Hidalgo, Javier Luis, Jiménez, Gema, Peran, Macarena, Martínez-González, Luis J., del Val, Coral, Zwir, Igor, Marchal, Juan Antonio, García, María Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072376/
https://www.ncbi.nlm.nih.gov/pubmed/32045987
http://dx.doi.org/10.3390/cancers12020379