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P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer

The GTPase Rac1 is a well-established master regulator of cell motility and invasiveness contributing to cancer metastasis. Dysregulation of the Rac1 signaling pathway, resulting in elevated motile and invasive potential, has been reported in multiple cancers. However, there are limited studies on t...

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Detalles Bibliográficos
Autores principales: Baker, Martin J., Abba, Martín C., Garcia-Mata, Rafael, Kazanietz, Marcelo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072377/
https://www.ncbi.nlm.nih.gov/pubmed/32092966
http://dx.doi.org/10.3390/cancers12020480