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Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer

Head and neck squamous cell carcinomas (HNSCC) affect more than 800,000 people annually worldwide, causing over 15,000 deaths in the US. Among HNSCC cancers, human papillomavirus (HPV)-negative HNSCC has the worst outcome, motivating efforts to improve therapy for this disease. The most common mutat...

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Detalles Bibliográficos
Autores principales: Deneka, Alexander Y., Einarson, Margret B., Bennett, John, Nikonova, Anna S., Elmekawy, Mohamed, Zhou, Yan, Lee, Jong Woo, Burtness, Barbara A., Golemis, Erica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072436/
https://www.ncbi.nlm.nih.gov/pubmed/32012873
http://dx.doi.org/10.3390/cancers12020306