Cargando…
Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer
Head and neck squamous cell carcinomas (HNSCC) affect more than 800,000 people annually worldwide, causing over 15,000 deaths in the US. Among HNSCC cancers, human papillomavirus (HPV)-negative HNSCC has the worst outcome, motivating efforts to improve therapy for this disease. The most common mutat...
Autores principales: | Deneka, Alexander Y., Einarson, Margret B., Bennett, John, Nikonova, Anna S., Elmekawy, Mohamed, Zhou, Yan, Lee, Jong Woo, Burtness, Barbara A., Golemis, Erica A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072436/ https://www.ncbi.nlm.nih.gov/pubmed/32012873 http://dx.doi.org/10.3390/cancers12020306 |
Ejemplares similares
-
Phospho-(T356)RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck
por: Beck, Tim N., et al.
Publicado: (2015) -
Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin
por: Gaponova, Anna V., et al.
Publicado: (2016) -
NEDD9 sustains hexokinase expression to promote glycolysis
por: Deneka, Alexander Y., et al.
Publicado: (2022) -
Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model
por: Deneka, Alexander Y., et al.
Publicado: (2017) -
Genomic insights into head and neck cancer
por: Beck, Tim N., et al.
Publicado: (2016)