Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

Hydrophobic bile salts are considered to promote liver fibrosis in cholestasis. However, evidence for this widely accepted hypothesis remains scarce. In established animal models of cholestasis, e.g., by Mdr2 knockout, cholestasis and fibrosis are both secondary to biliary damage. Therefore, to test...

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Detalles Bibliográficos
Autores principales: Hohenester, Simon, Kanitz, Veronika, Kremer, Andreas E., Paulusma, Coen C., Wimmer, Ralf, Kuehn, Helen, Denk, Gerald, Horst, David, Oude Elferink, Ronald, Beuers, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072501/
https://www.ncbi.nlm.nih.gov/pubmed/31979271
http://dx.doi.org/10.3390/cells9020281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072501/
https://www.ncbi.nlm.nih.gov/pubmed/31979271
http://dx.doi.org/10.3390/cells9020281

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