Synergistic Anti-Tumour Effect of Syk Inhibitor and Olaparib in Squamous Cell Carcinoma: Roles of Syk in EGFR Signalling and PARP1 Activation

Syk is a non-receptor tyrosine kinase involved in the signalling of immunoreceptors and growth factor receptors. Previously, we reported that Syk mediates epidermal growth factor receptor (EGFR) signalling and plays a negative role in the terminal differentiation of keratinocytes. To understand whet...

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Detalles Bibliográficos
Autores principales: Huang, Duen-Yi, Chen, Wei-Yu, Chen, Chi-Long, Wu, Nan-Lin, Lin, Wan-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072502/
https://www.ncbi.nlm.nih.gov/pubmed/32093123
http://dx.doi.org/10.3390/cancers12020489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072502/
https://www.ncbi.nlm.nih.gov/pubmed/32093123
http://dx.doi.org/10.3390/cancers12020489

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