FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major driver of invasion and metastasis and its upregulation is associated with poor patient prognosis. FAK is autoinhibited in th...

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Detalles Bibliográficos
Autores principales: Tapial Martínez, Paula, López Navajas, Pilar, Lietha, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072507/
https://www.ncbi.nlm.nih.gov/pubmed/31991559
http://dx.doi.org/10.3390/biom10020179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072507/
https://www.ncbi.nlm.nih.gov/pubmed/31991559
http://dx.doi.org/10.3390/biom10020179

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