An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability

Micronuclei are small, extranuclear bodies that are distinct from the primary cell nucleus. Micronucleus formation is an aberrant event that suggests a history of genotoxic stress or chromosome mis-segregation events. Accordingly, assays evaluating micronucleus formation serve as useful tools within...

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Detalles Bibliográficos
Autores principales: Lepage, Chloe C., Thompson, Laura L., Larson, Bradley, McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072510/
https://www.ncbi.nlm.nih.gov/pubmed/32024251
http://dx.doi.org/10.3390/cells9020344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072510/
https://www.ncbi.nlm.nih.gov/pubmed/32024251
http://dx.doi.org/10.3390/cells9020344

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