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Oncolytic Virus Encoding a Master Pro-Inflammatory Cytokine Interleukin 12 in Cancer Immunotherapy

Oncolytic viruses (OVs) are genetically modified or naturally occurring viruses, which preferentially replicate in and kill cancer cells while sparing healthy cells, and induce anti-tumor immunity. OV-induced tumor immunity can be enhanced through viral expression of anti-tumor cytokines such as int...

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Detalles Bibliográficos
Autores principales: Nguyen, Hong-My, Guz-Montgomery, Kirsten, Saha, Dipongkor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072539/
https://www.ncbi.nlm.nih.gov/pubmed/32050597
http://dx.doi.org/10.3390/cells9020400