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Increased Arginase Expression and Decreased Nitric Oxide in Pig Donor Lungs after Normothermic Ex Vivo Lung Perfusion

An established pig lung transplantation model was used to study the effects of cold ischemia time, normothermic acellular ex vivo lung perfusion (EVLP) and reperfusion after lung transplantation on l-arginine/NO metabolism in lung tissue. Lung tissue homogenates were analyzed for NO metabolite (NOx)...

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Detalles Bibliográficos
Autores principales: Tavasoli, Farshad, Liu, Mingyao, Machuca, Tiago, Bonato, Riccardo, Grant, David R., Cypel, Marcelo, Keshavjee, Shaf, Grasemann, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072555/
https://www.ncbi.nlm.nih.gov/pubmed/32075026
http://dx.doi.org/10.3390/biom10020300