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Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes

Immunosenescence in monocytes has been shown to be associated with several biochemical and functional changes, including development of senescence-associated secretory phenotype (SASP), which may be inhibited by klotho protein. To date, it was believed that SASP activation is associated with accumul...

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Detalles Bibliográficos
Autores principales: Mytych, Jennifer, Sołek, Przemysław, Będzińska, Agnieszka, Rusinek, Kinga, Warzybok, Aleksandra, Tabęcka-Łonczyńska, Anna, Koziorowski, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072557/
https://www.ncbi.nlm.nih.gov/pubmed/31972978
http://dx.doi.org/10.3390/cells9020261