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Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes
Immunosenescence in monocytes has been shown to be associated with several biochemical and functional changes, including development of senescence-associated secretory phenotype (SASP), which may be inhibited by klotho protein. To date, it was believed that SASP activation is associated with accumul...
Autores principales: | Mytych, Jennifer, Sołek, Przemysław, Będzińska, Agnieszka, Rusinek, Kinga, Warzybok, Aleksandra, Tabęcka-Łonczyńska, Anna, Koziorowski, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072557/ https://www.ncbi.nlm.nih.gov/pubmed/31972978 http://dx.doi.org/10.3390/cells9020261 |
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