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The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity

Thimet oligopeptidase (EC 3.4.24.15; EP24.15; THOP1) is a potential therapeutic target, as it plays key biological functions in processing biologically functional peptides. The structural conformation of THOP1 provides a unique restriction regarding substrate size, in that it only hydrolyzes peptide...

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Detalles Bibliográficos
Autores principales: Gewehr, Mayara C. F., Teixeira, Alexandre A. S., Santos, Bruna A. C., Biondo, Luana A., Gozzo, Fábio C., Cordibello, Amanda M., Eichler, Rosangela A. S., Reckziegel, Patrícia, Da Silva, Renée N. O., Dos Santos, Nilton B., Camara, Niels O. S., Castoldi, Angela, Barreto-Chaves, Maria L. M., Dale, Camila S., Senger, Nathalia, Lima, Joanna D. C. C., Seelaender, Marilia C. L., Inada, Aline C., Akamine, Eliana H., Castro, Leandro M., Rodrigues, Alice C., Rosa Neto, José C., Ferro, Emer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072564/
https://www.ncbi.nlm.nih.gov/pubmed/32079362
http://dx.doi.org/10.3390/biom10020321