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The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity
Thimet oligopeptidase (EC 3.4.24.15; EP24.15; THOP1) is a potential therapeutic target, as it plays key biological functions in processing biologically functional peptides. The structural conformation of THOP1 provides a unique restriction regarding substrate size, in that it only hydrolyzes peptide...
Autores principales: | Gewehr, Mayara C. F., Teixeira, Alexandre A. S., Santos, Bruna A. C., Biondo, Luana A., Gozzo, Fábio C., Cordibello, Amanda M., Eichler, Rosangela A. S., Reckziegel, Patrícia, Da Silva, Renée N. O., Dos Santos, Nilton B., Camara, Niels O. S., Castoldi, Angela, Barreto-Chaves, Maria L. M., Dale, Camila S., Senger, Nathalia, Lima, Joanna D. C. C., Seelaender, Marilia C. L., Inada, Aline C., Akamine, Eliana H., Castro, Leandro M., Rodrigues, Alice C., Rosa Neto, José C., Ferro, Emer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072564/ https://www.ncbi.nlm.nih.gov/pubmed/32079362 http://dx.doi.org/10.3390/biom10020321 |
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