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Decitabine Augments Chemotherapy-Induced PD-L1 Upregulation for PD-L1 Blockade in Colorectal Cancer

Programmed cell death-1 (PD-1) has demonstrated impressive clinical outcomes in several malignancies, but its therapeutic efficacy in the majority of colorectal cancers is still low. Therefore, methods to improve its therapeutic efficacy in colorectal cancer (CRC) patients need further investigation...

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Detalles Bibliográficos
Autores principales: Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Chen, William Tzu-Liang, Chen, Tsung-Wei, Hu, Ching-Han, Yang, Pei-Chen, Ke, Tao-Wei, Chao, K. S. Clifford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072566/
https://www.ncbi.nlm.nih.gov/pubmed/32079180
http://dx.doi.org/10.3390/cancers12020462