Poison-Exon Inclusion in DHX9 Reduces Its Expression and Sensitizes Ewing Sarcoma Cells to Chemotherapeutic Treatment

Alternative splicing is a combinatorial mechanism by which exons are joined to produce multiple mRNA variants, thus expanding the coding potential and plasticity of eukaryotic genomes. Defects in alternative splicing regulation are associated with several human diseases, including cancer. Ewing sarc...

Descripción completa

Detalles Bibliográficos
Autores principales: Palombo, Ramona, Verdile, Veronica, Paronetto, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072589/
https://www.ncbi.nlm.nih.gov/pubmed/32023846
http://dx.doi.org/10.3390/cells9020328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072589/
https://www.ncbi.nlm.nih.gov/pubmed/32023846
http://dx.doi.org/10.3390/cells9020328

Ejemplares similares