Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation

During chronic liver injury, hepatic stellate cells (HSC) undergo activation and are the principal cellular source of collagenous scar. In this study, we found that activation of mouse HSC (mHSC) was associated with a 4.5-fold increase in extracellular vesicle (EV) production and that fibrogenic gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xinlei, Chen, Ruju, Kemper, Sherri, Brigstock, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072607/
https://www.ncbi.nlm.nih.gov/pubmed/31991791
http://dx.doi.org/10.3390/cells9020290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072607/
https://www.ncbi.nlm.nih.gov/pubmed/31991791
http://dx.doi.org/10.3390/cells9020290

Ejemplares similares