Identification of PARP-1, Histone H1 and SIRT-1 as New Regulators of Breast Cancer-Related Aromatase Promoter I.3/II

Paracrine interactions between malignant estrogen receptor positive (ER(+)) breast cancer cells and breast adipose fibroblasts (BAFs) stimulate estrogen biosynthesis by aromatase in BAFs. In breast cancer, mainly the cAMP-responsive promoter I.3/II-region mediates excessive aromatase expression. A r...

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Detalles Bibliográficos
Autores principales: Kaiser, Alexander, Krüger, Thomas, Eiselt, Gabriele, Bechler, Joachim, Kniemeyer, Olaf, Huber, Otmar, Schmidt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072628/
https://www.ncbi.nlm.nih.gov/pubmed/32059481
http://dx.doi.org/10.3390/cells9020427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072628/
https://www.ncbi.nlm.nih.gov/pubmed/32059481
http://dx.doi.org/10.3390/cells9020427

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