CD22 Expression in B-Cell Acute Lymphoblastic Leukemia: Biological Significance and Implications for Inotuzumab Therapy in Adults

CD22 is a surface molecule expressed early during the ontogeny of B cells in the bone marrow and spleen, and can be found on B cells isolated from the different lymphoid compartments in humans. CD22 is expressed by most blasts from the majority (60–90%) of B-cell acute lymphoblastic leukemia (B-ALL)...

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Detalles Bibliográficos
Autores principales: Lanza, Francesco, Maffini, Enrico, Rondoni, Michela, Massari, Evita, Faini, Angelo Corso, Malavasi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072635/
https://www.ncbi.nlm.nih.gov/pubmed/32012891
http://dx.doi.org/10.3390/cancers12020303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072635/
https://www.ncbi.nlm.nih.gov/pubmed/32012891
http://dx.doi.org/10.3390/cancers12020303

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