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p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs

Arginase II reciprocally regulates endothelial nitric oxide synthase (eNOS) through a p32-dependent Ca(2+) control. We investigated the signaling pathway of arginase II-dependent eNOS phosphorylation. Western blot analysis was applied for examining protein activation and [Ca(2+)]c was analyzed by mi...

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Detalles Bibliográficos
Autores principales: Koo, Bon-Hyeock, Won, Moo-Ho, Kim, Young-Myeong, Ryoo, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072651/
https://www.ncbi.nlm.nih.gov/pubmed/32046324
http://dx.doi.org/10.3390/cells9020392