Cargando…

p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs

Arginase II reciprocally regulates endothelial nitric oxide synthase (eNOS) through a p32-dependent Ca(2+) control. We investigated the signaling pathway of arginase II-dependent eNOS phosphorylation. Western blot analysis was applied for examining protein activation and [Ca(2+)]c was analyzed by mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koo, Bon-Hyeock, Won, Moo-Ho, Kim, Young-Myeong, Ryoo, Sungwoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072651/ https://www.ncbi.nlm.nih.gov/pubmed/32046324 http://dx.doi.org/10.3390/cells9020392

Ejemplares similares

Arginase II protein regulates Parkin-dependent p32 degradation that contributes to Ca(2+)-dependent eNOS activation in endothelial cells
por: Koo, Bon-Hyeock, et al.
Publicado: (2021)

Arginase II inhibition prevents interleukin-8 production through regulation of p38 MAPK phosphorylation activated by loss of mitochondrial membrane potential in nLDL-stimulated hAoSMCs
por: Koo, Bon-Hyeock, et al.
Publicado: (2018)

Overexpressed p32 localized in the endoplasmic reticulum and mitochondria negatively regulates calcium-dependent endothelial nitric oxide synthase activity
por: Choi, Kwanhoon, et al.
Publicado: (2020)

Arginase II activity regulates cytosolic Ca(2+) level in a p32-dependent manner that contributes to Ca(2+)-dependent vasoconstriction in native low-density lipoprotein-stimulated vascular smooth muscle cells
por: Koo, Bon-hyeock, et al.
Publicado: (2019)

Arginase inhibition by rhaponticin increases L-arginine concentration that contributes to Ca(2+)-dependent eNOS activation
por: Koo, Bon-Hyeock, et al.
Publicado: (2021)

Arginase II Contributes to the Ca(2+)/CaMKII/eNOS Axis by Regulating Ca(2+) Concentration Between the Cytosol and Mitochondria in a p32‐Dependent Manner
por: Koo, Bon‐Hyeock, et al.
Publicado: (2018)

Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice
por: Shin, Woosung, et al.
Publicado: (2012)

Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling
por: Shin, Woosung, et al.
Publicado: (2013)

Arginase Inhibition Suppresses Native Low-Density Lipoprotein-Stimulated Vascular Smooth Muscle Cell Proliferation by NADPH Oxidase Inactivation
por: Koo, Bon-Hyeock, et al.
Publicado: (2018)

Arginase Inhibition Restores Peroxynitrite-Induced Endothelial Dysfunction via L-Arginine-Dependent Endothelial Nitric Oxide Synthase Phosphorylation
por: Nguyen, Minh Cong, et al.
Publicado: (2016)

Cyclosporin-A reduced the cytotoxicity of propranolol in HUVECs via p38 MAPK signaling
por: Lv, Zhong, et al.
Publicado: (2022)

The Involvement of Arginase and Nitric Oxide Synthase in Breast Cancer Development: Arginase and NO Synthase as Therapeutic Targets in Cancer
por: Avtandilyan, Nikolay, et al.
Publicado: (2018)

Endothelial arginase II and atherosclerosis
por: Ryoo, Sungwoo, et al.
Publicado: (2011)

The Volatile Oil of Nardostachyos Radix et Rhizoma Induces Endothelial Nitric Oxide Synthase Activity in HUVEC Cells
por: Maiwulanjiang, Maitinuer, et al.
Publicado: (2015)

p38γ and p38δ Mitogen Activated Protein Kinases (MAPKs), New Stars in the MAPK Galaxy
por: Escós, Alejandra, et al.
Publicado: (2016)

Arginase II inhibitory activity of flavonoid compounds from Scutellaria indica
por: Kim, Sang Won, et al.
Publicado: (2013)

Stabilization of F-Actin Cytoskeleton by Paclitaxel Improves the Blastocyst Developmental Competence through P38 MAPK Activity in Porcine Embryos
por: Joe, Seung-Yeon, et al.
Publicado: (2022)

MKP-3 suppresses LPS-induced inflammatory responses in HUVECs via inhibition of p38 MAPK/NF-κB pathway
por: Unenkhuu, Banzragchgarav, et al.
Publicado: (2021)

Korean Red Ginseng Water Extract Restores Impaired Endothelial Function by Inhibiting Arginase Activity in Aged Mice
por: Choi, Kwanhoon, et al.
Publicado: (2014)

Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice
por: Nguyen, Minh Cong, et al.
Publicado: (2017)

Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-κB and JNK/p38 MAPK activation pathways
por: Hsieh, I-Ni, et al.
Publicado: (2011)

p38 MAPK in MDS
por: Gañán‐Gómez, Irene, et al.
Publicado: (2015)

TIRAP-mediated activation of p38 MAPK in inflammatory signaling
por: Rajpoot, Sajjan, et al.
Publicado: (2022)

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
por: Rath, Meera, et al.
Publicado: (2014)

Multitracer Stable Isotope Quantification of Arginase and Nitric Oxide Synthase Activity in a Mouse Model of Pseudomonas Lung Infection
por: Grasemann, Hartmut, et al.
Publicado: (2014)

p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-Uncoupling in Obesity
por: Yu, Yi, et al.
Publicado: (2014)

Immunostimulated enterocytes activate extracellular arginase I which competes with enterocyte inducible nitric oxide synthase for arginine during inflammation
por: Miki, K, et al.
Publicado: (2009)

Activation of p38MAPK Contributes to Expanded Polyglutamine-Induced Cytotoxicity
por: Tsirigotis, Maria, et al.
Publicado: (2008)

Inhibition of LPS-Induced Activation of Coagulation by p38 MAPK Inhibitor
por: Koch, Lutz, et al.
Publicado: (2012)

Evidence for the Involvement of p38 MAPK Activation in Barnacle Larval Settlement
por: He, Li-Sheng, et al.
Publicado: (2012)

Dehydrocorydaline promotes myogenic differentiation via p38 MAPK activation
por: Yoo, Miran, et al.
Publicado: (2016)

Prions activate a p38 MAPK synaptotoxic signaling pathway
por: Fang, Cheng, et al.
Publicado: (2018)

Virus-induced p38 MAPK activation facilitates viral infection
por: Cheng, Yuting, et al.
Publicado: (2020)

New Insights into the p38γ and p38δ MAPK Pathways
por: Risco, Ana, et al.
Publicado: (2012)

LZAP Inhibits p38 MAPK (p38) Phosphorylation and Activity by Facilitating p38 Association with the Wild-Type p53 Induced Phosphatase 1 (WIP1)
por: An, Hanbing, et al.
Publicado: (2011)

TIPE2 Negatively Regulates Inflammation by Switching Arginine Metabolism from Nitric Oxide Synthase to Arginase
por: Lou, Yunwei, et al.
Publicado: (2014)

Aluminum Nanoparticles Induce ERK and p38MAPK Activation in Rat Brain
por: Kwon, Jung-Taek, et al.
Publicado: (2013)

Activated p38 MAPK in Peripheral Blood Monocytes of Steroid Resistant Asthmatics
por: Li, Ling-bo, et al.
Publicado: (2015)

Immunomodulatory Effects of Colistin on Macrophages in Rats by Activating the p38/MAPK Pathway
por: Wang, Jin, et al.
Publicado: (2019)

The p38 MAPK Signaling Activation in Colorectal Cancer upon Therapeutic Treatments
por: Pranteda, Angelina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_thvmvv54prv3f4sj6t49tn6778