Hypoxia-Induced Centrosome Amplification Underlies Aggressive Disease Course in HPV-Negative Oropharyngeal Squamous Cell Carcinomas

Human papillomavirus-negative (HPV-neg) oropharyngeal squamous cell carcinomas (OPSCCs) are associated with poorer overall survival (OS) compared with HPV-positive (HPV-pos) OPSCCs. The major obstacle in improving outcomes of HPV-neg patients is the lack of robust biomarkers and therapeutic targets....

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Detalles Bibliográficos
Autores principales: Mittal, Karuna, Choi, Da Hoon, Wei, Guanhao, Kaur, Jaspreet, Klimov, Sergey, Arora, Komal, Griffith, Christopher C., Kumar, Mukesh, Imhansi-Jacob, Precious, Melton, Brian D., Bhimji-Pattni, Sonal, Osan, Remus M., Rida, Padmashree, Golusinski, Paweł, Aneja, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072660/
https://www.ncbi.nlm.nih.gov/pubmed/32102296
http://dx.doi.org/10.3390/cancers12020517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072660/
https://www.ncbi.nlm.nih.gov/pubmed/32102296
http://dx.doi.org/10.3390/cancers12020517

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