N(6)-Adenosine Methylation in RNA and a Reduced m(3)G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions

The DNA damage response is mediated by both DNA repair proteins and epigenetic markers. Here, we observe that N(6)-methyladenosine (m(6)A), a mark of the epitranscriptome, was common in RNAs accumulated at UV-damaged chromatin; however, inhibitors of RNA polymerases I and II did not affect the m(6)A...

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Detalles Bibliográficos
Autores principales: Svobodová Kovaříková, Alena, Stixová, Lenka, Kovařík, Aleš, Komůrková, Denisa, Legartová, Soňa, Fagherazzi, Paolo, Bártová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072662/
https://www.ncbi.nlm.nih.gov/pubmed/32033081
http://dx.doi.org/10.3390/cells9020360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072662/
https://www.ncbi.nlm.nih.gov/pubmed/32033081
http://dx.doi.org/10.3390/cells9020360

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