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Impaired Nuclear Export of the Ribonucleoprotein Complex and Virus-Induced Cytotoxicity Combine to Restrict Propagation of the A/Duck/Malaysia/02/2001 (H9N2) Virus in Human Airway Cells

In humans, (A549) cells impaired H9N2 virus nuclear export of the ribonucleoprotein (RNP) complex contrasted with the early and efficient nuclear export of the H1N1/WSN and pH1N1 virus RNP complexes. Although nuclear export of the RNP complex occurred via the nuclear pore complex, H9N2 virus infecti...

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Detalles Bibliográficos
Autores principales: Kumar, Sriram, Yeo, Dawn, Harur Muralidharan, Nisha, Lai, Soak Kuan, Tong, Cathlyn, Tan, Boon Huan, Sugrue, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072679/
https://www.ncbi.nlm.nih.gov/pubmed/32028682
http://dx.doi.org/10.3390/cells9020355