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The Potential of Telomeric G-Quadruplexes Containing Modified Oligoguanosine Overhangs in Activation of Bacterial Phagocytosis and Leukotriene Synthesis in Human Neutrophils

Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes. Using HPLC analysis, flow cytometry, and other biochemical methods, we stud...

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Detalles Bibliográficos
Autores principales: Golenkina, Ekaterina A., Viryasova, Galina M., Dolinnaya, Nina G., Bannikova, Valeria A., Gaponova, Tatjana V., Romanova, Yulia M., Sud’ina, Galina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072695/
https://www.ncbi.nlm.nih.gov/pubmed/32041263
http://dx.doi.org/10.3390/biom10020249