A Genetic Polymorphism in the Pannexin1 Gene Predisposes for The Development of Endothelial Dysfunction with Increasing BMI

Endothelial dysfunction worsens when body mass index (BMI) increases. Pannexin1 (Panx1) ATP release channels regulate endothelial function and lipid homeostasis in mice. We investigated whether the Panx1-400A>C single nucleotide polymorphism (SNP), encoding for a gain-of-function channel, associa...

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Detalles Bibliográficos
Autores principales: Molica, Filippo, Quercioli, Alessandra, Montecucco, Fabrizio, Schindler, Thomas H., Kwak, Brenda R., Morel, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072696/
https://www.ncbi.nlm.nih.gov/pubmed/32023876
http://dx.doi.org/10.3390/biom10020208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072696/
https://www.ncbi.nlm.nih.gov/pubmed/32023876
http://dx.doi.org/10.3390/biom10020208

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