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Impact of JNK and Its Substrates on Dendritic Spine Morphology

The protein kinase JNK1 exhibits high activity in the developing brain, where it regulates dendrite morphology through the phosphorylation of cytoskeletal regulatory proteins. JNK1 also phosphorylates dendritic spine proteins, and Jnk1-/- mice display a long-term depression deficit. Whether JNK1 or...

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Detalles Bibliográficos
Autores principales: Komulainen, Emilia, Varidaki, Artemis, Kulesskaya, Natalia, Mohammad, Hasan, Sourander, Christel, Rauvala, Heikki, Coffey, Eleanor T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072711/
https://www.ncbi.nlm.nih.gov/pubmed/32074971
http://dx.doi.org/10.3390/cells9020440