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Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer
The mechanistic target of rapamycin (mTOR) is a master regulator of protein translation, metabolism, cell growth and proliferation. It forms two complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 is frequently deregulated in many cancers, including breast cancer, and is an important target fo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072743/ https://www.ncbi.nlm.nih.gov/pubmed/32054043 http://dx.doi.org/10.3390/ijms21041199 |