The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord

Understanding the cellular and molecular basis of selective vulnerability has been challenging, especially for motor neuron diseases. Developing drugs that improve the health of neurons that display selective vulnerability relies on in vivo cell-based models and quantitative readout measures that tr...

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Detalles Bibliográficos
Autores principales: Genc, Baris, Gozutok, Oge, Kocak, Nuran, Ozdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072754/
https://www.ncbi.nlm.nih.gov/pubmed/32098365
http://dx.doi.org/10.3390/cells9020502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072754/
https://www.ncbi.nlm.nih.gov/pubmed/32098365
http://dx.doi.org/10.3390/cells9020502

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