Loss of 5′-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness

The 5’-methylthioadenosine phosphorylase (MTAP) gene is located in the chromosomal region 9p21. MTAP deletion is a frequent event in a wide variety of human cancers; however, its biological role in tumorigenesis remains unclear. The purpose of this study was to characterize the MTAP expression profi...

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Detalles Bibliográficos
Autores principales: de Menezes, Weder Pereira, Silva, Viviane Aline Oliveira, Gomes, Izabela Natália Faria, Rosa, Marcela Nunes, Spina, Maria Luisa Corcoll, Carloni, Adriana Cruvinel, Alves, Ana Laura Vieira, Melendez, Matias, Almeida, Gisele Caravina, da Silva, Luciane Sussuchi, Clara, Carlos, da Cunha, Isabela Werneck, Hajj, Glaucia Noeli Maroso, Jones, Chris, Bidinotto, Lucas Tadeu, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072758/
https://www.ncbi.nlm.nih.gov/pubmed/32093414
http://dx.doi.org/10.3390/cells9020492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072758/
https://www.ncbi.nlm.nih.gov/pubmed/32093414
http://dx.doi.org/10.3390/cells9020492

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