The Vacuolar H(+) ATPase α3 Subunit Negatively Regulates Migration and Invasion of Human Pancreatic Ductal Adenocarcinoma Cells

Increased metabolic acid production and upregulation of net acid extrusion render pH homeostasis profoundly dysregulated in many cancers. Plasma membrane activity of vacuolar H(+) ATPases (V-ATPases) has been implicated in acid extrusion and invasiveness of some cancers, yet often on the basis of un...

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Detalles Bibliográficos
Autores principales: Flinck, Mette, Hagelund, Sofie, Gorbatenko, Andrej, Severin, Marc, Pedraz-Cuesta, Elena, Novak, Ivana, Stock, Christian, Pedersen, Stine Falsig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072798/
https://www.ncbi.nlm.nih.gov/pubmed/32085585
http://dx.doi.org/10.3390/cells9020465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072798/
https://www.ncbi.nlm.nih.gov/pubmed/32085585
http://dx.doi.org/10.3390/cells9020465

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