Tissue Distribution and Receptor Activation by Somapacitan, a Long Acting Growth Hormone Derivative

Somapacitan is a long-acting, once-weekly, albumin-binding growth hormone (GH) derivative. The reversible albumin-binding properties leads to prolonged circulation half-life. Here, we investigated and compared somapacitan with human GH on downstream receptor signaling in primary hepatocytes and hepa...

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Detalles Bibliográficos
Autores principales: Petersen, Maj, Gandhi, Prafull S., Buchardt, Jens, Alanentalo, Tomas, Fels, Johannes Josef, Johansen, Nils Langeland, Helding-Kvist, Peter, Vad, Knud, Thygesen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072805/
https://www.ncbi.nlm.nih.gov/pubmed/32053994
http://dx.doi.org/10.3390/ijms21041181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072805/
https://www.ncbi.nlm.nih.gov/pubmed/32053994
http://dx.doi.org/10.3390/ijms21041181

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