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Tissue Distribution and Receptor Activation by Somapacitan, a Long Acting Growth Hormone Derivative

Somapacitan is a long-acting, once-weekly, albumin-binding growth hormone (GH) derivative. The reversible albumin-binding properties leads to prolonged circulation half-life. Here, we investigated and compared somapacitan with human GH on downstream receptor signaling in primary hepatocytes and hepa...

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Detalles Bibliográficos
Autores principales:	Petersen, Maj, Gandhi, Prafull S., Buchardt, Jens, Alanentalo, Tomas, Fels, Johannes Josef, Johansen, Nils Langeland, Helding-Kvist, Peter, Vad, Knud, Thygesen, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072805/ https://www.ncbi.nlm.nih.gov/pubmed/32053994 http://dx.doi.org/10.3390/ijms21041181

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