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WNK2 Inhibits Autophagic Flux in Human Glioblastoma Cell Line

Autophagy is a cell-survival pathway with dual role in tumorigenesis, promoting either tumor survival or tumor death. WNK2 gene, a member of the WNK (with no lysine (K)) subfamily, acts as a tumor suppressor gene in gliomas, regulating cell migration and invasion; however, its role in autophagy proc...

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Detalles Bibliográficos
Autores principales: Alves, Ana Laura Vieira, Costa, Angela Margarida, Martinho, Olga, da Silva, Vinicius Duval, Jordan, Peter, Silva, Viviane Aline Oliveira, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072831/
https://www.ncbi.nlm.nih.gov/pubmed/32093151
http://dx.doi.org/10.3390/cells9020485