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NOTO Transcription Factor Directs Human Induced Pluripotent Stem Cell-Derived Mesendoderm Progenitors to a Notochordal Fate

The founder cells of the Nucleus pulposus, the centre of the intervertebral disc, originate in the embryonic notochord. After birth, mature notochordal cells (NC) are identified as key regulators of disc homeostasis. Better understanding of their biology has great potential in delaying the onset of...

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Detalles Bibliográficos
Autores principales: Colombier, Pauline, Halgand, Boris, Chédeville, Claire, Chariau, Caroline, François-Campion, Valentin, Kilens, Stéphanie, Vedrenne, Nicolas, Clouet, Johann, David, Laurent, Guicheux, Jérôme, Camus, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072849/
https://www.ncbi.nlm.nih.gov/pubmed/32102328
http://dx.doi.org/10.3390/cells9020509