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Microtubule-Mediated NLRP3 Inflammasome Activation Is Independent of Microtubule-Associated Innate Immune Factor GEF-H1 in Murine Macrophages

Inflammasomes are intracellular multiple protein complexes that mount innate immune responses to tissue damage and invading pathogens. Their excessive activation is crucial in the development and pathogenesis of inflammatory disorders. Microtubules have been reported to provide the platform for medi...

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Detalles Bibliográficos
Autores principales: Lai, Hsuan-Ju, Hsu, Yi-Hsuan, Lee, Guan-Ying, Chiang, Hao-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072875/
https://www.ncbi.nlm.nih.gov/pubmed/32075101
http://dx.doi.org/10.3390/ijms21041302