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Microtubule-Mediated NLRP3 Inflammasome Activation Is Independent of Microtubule-Associated Innate Immune Factor GEF-H1 in Murine Macrophages
Inflammasomes are intracellular multiple protein complexes that mount innate immune responses to tissue damage and invading pathogens. Their excessive activation is crucial in the development and pathogenesis of inflammatory disorders. Microtubules have been reported to provide the platform for medi...
Autores principales: | Lai, Hsuan-Ju, Hsu, Yi-Hsuan, Lee, Guan-Ying, Chiang, Hao-Sen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072875/ https://www.ncbi.nlm.nih.gov/pubmed/32075101 http://dx.doi.org/10.3390/ijms21041302 |
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