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Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology

Apolipoprotein E (APOE) ε4 gene allele and type 2 diabetes mellitus (T2DM) are prime risk factors for Alzheimer’s disease (AD). Despite evidence linking T2DM and apoE4, the mechanism underlying their interaction is yet to be determined. In the present study, we employed a model of APOE-targeted repl...

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Detalles Bibliográficos
Autores principales: Koren-Iton, Amit, Salomon-Zimri, Shiran, Smolar, Alex, Shavit-Stein, Efrat, Dori, Amir, Chapman, Joab, Michaelson, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072920/
https://www.ncbi.nlm.nih.gov/pubmed/32075060
http://dx.doi.org/10.3390/ijms21041289