Cargando…
Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology
Apolipoprotein E (APOE) ε4 gene allele and type 2 diabetes mellitus (T2DM) are prime risk factors for Alzheimer’s disease (AD). Despite evidence linking T2DM and apoE4, the mechanism underlying their interaction is yet to be determined. In the present study, we employed a model of APOE-targeted repl...
Autores principales: | Koren-Iton, Amit, Salomon-Zimri, Shiran, Smolar, Alex, Shavit-Stein, Efrat, Dori, Amir, Chapman, Joab, Michaelson, Daniel M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072920/ https://www.ncbi.nlm.nih.gov/pubmed/32075060 http://dx.doi.org/10.3390/ijms21041289 |
Ejemplares similares
-
Complement and Coagulation System Crosstalk in Synaptic and Neural Conduction in the Central and Peripheral Nervous Systems
por: Berkowitz, Shani, et al.
Publicado: (2021) -
Behavioral testing affects the phenotypic expression of APOE ε3 and APOE ε4 in targeted replacement mice and reduces the differences between them
por: Salomon-Zimri, Shiran, et al.
Publicado: (2015) -
Prolonged systemic inflammation persistently modifies synaptic plasticity in the hippocampus: modulation by the stress hormones
por: Maggio, Nicola, et al.
Publicado: (2013) -
The role of thrombin in the pathogenesis of diabetic neuropathy
por: Shavit-Stein, Efrat, et al.
Publicado: (2019) -
Neuroprotective Effect of Glatiramer Acetate on Neurofilament Light Chain Leakage and Glutamate Excess in an Animal Model of Multiple Sclerosis
por: Aharoni, Rina, et al.
Publicado: (2021)