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Dynamic Behavior of p53 Driven by Delay and a Microrna-34a-Mediated Feedback Loop
The tumor suppressor protein p53 is a critical hub in the comprehensive transcriptional network that inhibits the growth of cells after acute stress stimulation. In this paper, an integrated model of the p53 signaling pathway in response to DNA damage is proposed and the p53 stability and oscillator...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072921/ https://www.ncbi.nlm.nih.gov/pubmed/32070036 http://dx.doi.org/10.3390/ijms21041271 |