Cargando…

Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation

Doxorubicin (DOX) is an effective chemotherapeutic agent used to treat a wide variety of malignancies. In addition to its multi-organ toxicity, DOX treatment has been shown to induce systemic inflammation in patients and experimental animals. Inflammation alters the expression of hepatic cytochrome...

Descripción completa

Detalles Bibliográficos
Autores principales: Grant, Marianne K.O., Abdelgawad, Ibrahim Y., Lewis, Christine A., Zordoky, Beshay N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072970/
https://www.ncbi.nlm.nih.gov/pubmed/32074957
http://dx.doi.org/10.3390/ijms21041279