Cargando…
Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation
Doxorubicin (DOX) is an effective chemotherapeutic agent used to treat a wide variety of malignancies. In addition to its multi-organ toxicity, DOX treatment has been shown to induce systemic inflammation in patients and experimental animals. Inflammation alters the expression of hepatic cytochrome...
Autores principales: | Grant, Marianne K.O., Abdelgawad, Ibrahim Y., Lewis, Christine A., Zordoky, Beshay N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072970/ https://www.ncbi.nlm.nih.gov/pubmed/32074957 http://dx.doi.org/10.3390/ijms21041279 |
Ejemplares similares
-
Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice
por: Grant, Marianne K. O., et al.
Publicado: (2019) -
Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction
por: Grant, Marianne K. O., et al.
Publicado: (2020) -
Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice
por: Grant, Marianne K. O., et al.
Publicado: (2017) -
Doxorubicin Paradoxically Ameliorates Tumor-Induced Inflammation in Young Mice
por: Abdelgawad, Ibrahim Y., et al.
Publicado: (2021) -
Metformin mitigates SASP secretion and LPS-triggered hyper-inflammation in Doxorubicin-induced senescent endothelial cells
por: Abdelgawad, Ibrahim Y., et al.
Publicado: (2023)