Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells

Doxorubicin (DXR) is a drug widely used in chemotherapy. Its mode of action is based on its intercalation properties, involving the inhibition of topoisomerase II. However, few studies have reported the mitochondrial effects of DXR while investigating cardiac toxicity induced by the treatment, mostl...

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Detalles Bibliográficos
Autores principales: Bellance, Nadège, Furt, Fabienne, Melser, Su, Lalou, Claude, Thoraval, Didier, Maneta-Peyret, Lilly, Lacombe, Didier, Moreau, Patrick, Rossignol, Rodrigue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072979/
https://www.ncbi.nlm.nih.gov/pubmed/32075281
http://dx.doi.org/10.3390/ijms21041317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072979/
https://www.ncbi.nlm.nih.gov/pubmed/32075281
http://dx.doi.org/10.3390/ijms21041317

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