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Hypoxia-Dependent Expression of TG2 Isoforms in Neuroblastoma Cells as Consequence of Different MYCN Amplification Status

Transglutaminase 2 (TG2) is a multifunctional enzyme and two isoforms, TG2-L and TG2-S, exerting opposite effects in the regulation of cell death and survival, have been revealed in cancer tissues. Notably, in cancer cells a hypoxic environment may stimulate tumor growth, invasion and metastasis. He...

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Detalles Bibliográficos
Autores principales: Currò, Monica, Ferlazzo, Nadia, Giunta, Maria Laura, Montalto, Angela Simona, Russo, Tiziana, Arena, Salvatore, Impellizzeri, Pietro, Caccamo, Daniela, Romeo, Carmelo, Ientile, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072980/
https://www.ncbi.nlm.nih.gov/pubmed/32085516
http://dx.doi.org/10.3390/ijms21041364