TLR4 Stimulation Promotes Human AVIC Fibrogenic Activity through Upregulation of Neurotrophin 3 Production

Background: Calcific aortic valve disease (CAVD) is a chronic inflammatory disease that manifests as progressive valvular fibrosis and calcification. An inflammatory milieu in valvular tissue promotes fibrosis and calcification. Aortic valve interstitial cell (AVIC) proliferation and the over-produc...

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Detalles Bibliográficos
Autores principales: Yao, Qingzhou, The, Erlinda, Ao, Lihua, Zhai, Yufeng, Osterholt, Maren K., Fullerton, David A., Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072994/
https://www.ncbi.nlm.nih.gov/pubmed/32074942
http://dx.doi.org/10.3390/ijms21041276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072994/
https://www.ncbi.nlm.nih.gov/pubmed/32074942
http://dx.doi.org/10.3390/ijms21041276

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