Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells

The overexpressing ABCB1 transporter is one of the key factors leading to multidrug resistance (MDR). Thus, many ABCB1 inhibitors have been found to be able to overcome ABCB1-mediated MDR. However, some inhibitors also work as a substrate of ABCB1, which indicates that in order to achieve an effecti...

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Detalles Bibliográficos
Autores principales: Wang, Jingqiu, Yang, Dong-Hua, Yang, Yuqi, Wang, Jing-Quan, Cai, Chao-Yun, Lei, Zi-Ning, Teng, Qiu-Xu, Wu, Zhuo-Xun, Zhao, Linguo, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073023/
https://www.ncbi.nlm.nih.gov/pubmed/32092870
http://dx.doi.org/10.3390/ijms21041387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073023/
https://www.ncbi.nlm.nih.gov/pubmed/32092870
http://dx.doi.org/10.3390/ijms21041387

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