Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt

Ceramide kinase (CerK) is a lipid kinase that converts the proapoptotic ceramide to ceramide 1-phosphate, which has been proposed to have pro-malignant properties and regulate cell responses such as proliferation, migration, and inflammation. We used the parental human breast cancer cell line MDA-MB...

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Detalles Bibliográficos
Autores principales: Schwalm, Stephanie, Erhardt, Martin, Römer, Isolde, Pfeilschifter, Josef, Zangemeister-Wittke, Uwe, Huwiler, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073039/
https://www.ncbi.nlm.nih.gov/pubmed/32092937
http://dx.doi.org/10.3390/ijms21041396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073039/
https://www.ncbi.nlm.nih.gov/pubmed/32092937
http://dx.doi.org/10.3390/ijms21041396

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