Galectin 3 Deficiency Alters Chondrocyte Primary Cilium Formation and Exacerbates Cartilage Destruction via Mitochondrial Apoptosis

Mechanical overload and aging are the main risk factors of osteoarthritis (OA). Galectin 3 (GAL3) is important in the formation of primary cilia, organelles that are able to sense mechanical stress. The objectives were to evaluate the role of GAL3 in chondrocyte primary cilium formation and in OA in...

Descripción completa

Detalles Bibliográficos
Autores principales: Hafsia, Narjès, Forien, Marine, Renaudin, Félix, Delacour, Delphine, Reboul, Pascal, Van Lent, Peter, Cohen-Solal, Martine, Lioté, Frédéric, Poirier, Françoise, Ea, Hang Korng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073077/
https://www.ncbi.nlm.nih.gov/pubmed/32098291
http://dx.doi.org/10.3390/ijms21041486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073077/
https://www.ncbi.nlm.nih.gov/pubmed/32098291
http://dx.doi.org/10.3390/ijms21041486

Ejemplares similares